Vancomycin Tool

THIS SERVICE IS PROVIDED “AS IS” AND “AS AVAILABLE,” WITHOUT ANY WARRANTY OR GUARANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED. MEDSAFER AND ANY OF THE DEVELOPERS OF THIS TOOL ARE NEITHER RESPONSIBLE NOR LIABLE FOR ANY INDIRECT, INCIDENTAL, CONSEQUENTIAL, SPECIAL, EXEMPLARY, PUNITIVE OR OTHER DAMAGES ARISING OUT OF OR RELATING IN ANY WAY TO USE OF THE SERVICE. YOUR USE OF THE SERVICE SERVES AS YOUR ACCEPTANCE OF THESE TERMS.

Changelog:

Version 1.23

• Adjusted initial Vd to use 0.8L/kg in underweight and normal weight patients and 0.7kg/L (using adjusted body weight)
• Adjusted Clearance - Now using method proposed by Fewel in place of Bauer (but leave Bauer for comparison)

Version 1.22

• Now available to general public

Version 1.21

• Fixed bug with entry of dates and times. Will now only accept valid dates/times and some basic error checking
• Added a cell which turns red if there appears to be an error with the dates/times despite the data entry restrictions
• Changed initial dosing volume of distribution in patients above ideal body weight. Previously had used 0.7*(IBW + 0.5(WT-IBW) but now it is using 0.75*ABW.
• Modified creatinine clearance formula -- now using adjusted body weight if weight >15% above IBW. Previously had used the Salazar-Corcoran equation.

Version 1.2

• 2-level adjustment now based on dates and times as opposed to user manually calculated number of hours
• Allow troughs to be slightly below 10 (although generally not preferred due to concern for resistance selection, it allows for some necessary flexibility)

Version 1.1

• Optimization of automatic dose selection to account for target AUC 600-800
• Bugfixes for identification of off target values
• Separation to separate pages for ease of use

Version 1.0

• Initial release of initial dose calculator and 2 level adjustment